1 Note: the scientific research presented herein is intended to help further understand the ingredients of the Edge7 products and are not intended as implicit claims of efficacy.

2 Ruhé HG, Mason NS, Schene AH. Mood is indirectly related to serotonin, norepinephrine and dopamine levels in humans: a meta-analysis of monoamine depletion studies. Mol Psychiatry. 2007;12(4):331-359.doi:10.1038/sj.mp.4001949.

3 Deijen J., Orlebeke J. Effect of tyrosine on cognitive function and blood pressure under stress. Brain Res Bull. 1994;33(3):319-323. doi:10.1016/0361-9230(94)90200-3.

4 Neri DF, Wiegmann D, Stanny RR, Shappell SA, McCardie A, McKay DL. The effects of tyrosine on cognitive performance during extended wakefulness. Aviat Space Environ Med. 1995;66(4):313-319

5 Deijen J., Wientjes CJ.,Vullinghs HF., Cloin P., Langefeld J. Tyrosine improves cognitive performance and reduces blood pressure in cadets after one week of a combat training course. Brain Res Bull. 1999;48(2):203-209. doi:10.1016/S0361-9230(98)00163-4.

6 Mahoney CR, Castellani J, Kramer FM, Young A, Lieberman HR. Tyrosine supplementation mitigates working memory decrements during cold exposure. PhysiolBehav. 2007;92(4):575-582. doi:10.1016/j.physbeh.2007.05.003.

7 Gelenberg AJ, Wojcik JD, Gibson CJ, Wurtman RJ. Tyrosine for depression.J Psychiatr Res. 17(2):175-180.

8 Ramdani C, Carbonnell L, Vidal F, Béranger C, Dagher A, Hasbroucq T. Dopamine precursors depletion impairs impulse control in healthy volunteers. Psychopharmacology (Berl). 2015;232(2):477-487. doi:10.1007/s00213-014-3686-z.

9 Hinz M, Stein A, Neff R, Weinberg R, Uncini T. Treatment of attention deficit hyperactivity disorder with monoamine amino acid precursors and organic cation transporter assay interpretation. Neuropsychiatr Dis Treat. 2011;7:31-38. doi:10.2147/NDT.S16270.

10 Owen GN, Parnell H, De Bruin EA, Rycroft JA. The combined effects of L-theanine and caffeine on cognitive performance and mood.NutrNeurosci. 2008;11(4):193-198. doi:10.1179/147683008X301513.

11 Haskell CF, Kennedy DO, Milne AL, Wesnes KA, Scholey AB. The effects of L-theanine, caffeine and their combination on cognition and mood.Biol Psychol. 2008;77(2):113-122. doi:10.1016/j.biopsycho.2007.09.008.

12 Mednick SC, Cai DJ, Kanady J, Drummond SPA. Comparing the benefits of caffeine, naps and placebo on verbal, motor and perceptual memory. Behav Brain Res. 2008;193(1):79-86. doi:10.1016/j.bbr.2008.04.028.

13 Huang Z-L, Qu W-M, Eguchi N, et al. Adenosine A2A, but not A1, receptors mediate the arousal effect of caffeine. Nat Neurosci. 2005;8(7):858-859. doi:10.1038/nn1491.

14 Higgins GA, Grzelak ME, Pond AJ, Cohen-Williams ME, Hodgson RA, Varty GB. The effect of caffeine to increase reaction time in the rat during a test of attention is mediated through antagonism of adenosine A2A receptors. Behav Brain Res. 2007;185(1):32-42. doi:10.1016/j.bbr.2007.07.013.

15 Einöther SJL, Giesbrecht T. Caffeine as an attention enhancer: reviewing existing assumptions. Psychopharmacology (Berl). 2013;225(2):251-274. doi:10.1007/s00213-012-2917-4.

16 Lakhan SE, Vieira KF. Nutritional and herbal supplements for anxiety and anxiety-related disorders: systematic review.Nutr J. 2010;9:42. doi:10.1186/1475-2891-9-42.

17 Hasani N, Kazemi M, KarimiAfshar H, Kazemi M, Tavakoli M. Comparison of the Effects of Relaxation and Vitamin B6 on Emotional and Physical Symptoms in Premenstrual Syndrome. Evid Based Care. 2015;5(2):75-83.